- Cancerkin’s Theatre Evening 6 October 2014!
- Darkness at night key to success of tamoxifen treatment
Seminar is Cancerkin’s Theatre Evening on Monday 6 October 2014!
We have just received the good news from the Hampstead Theatre that this year, Cancerkin’s theatre evening in support of Breast Cancer Awareness Month will take place on Monday 6 October 2014. Pulitzer Prize nominee Theresa Rebeck‘s mordant comedy Seminar is a sparkling cocktail of ambition, power and lust – and one with an unexpected kick.
‘Life is complicated. People are complicated. If you can’t figure that out, you’ll never be much of a writer.’
Four aspiring young writers have paid big bucks to seek wisdom at the feet of the fearsome Leonard – once a celebrated novelist, now a cantankerous editor, teacher and grandstanding chronicler of third-world war zones…Under Leonard’s recklessly brilliant but brutally unorthodox tuition, competition for his approval is intense and the students clash. Alliances are made and broken, tactical schemes are hatched – how far are they willing to go to make it to the top?
Seminar is directed by Terry Johnson following his critically acclaimed Hysteria last year starring Antony Sher which was so popular with Cancerkin supporters. His other recent hits at Hampstead include Race by David Mamet and Old Money starring Maureen Lipman.
Tickets can be bought directly from Cancerkin and include a drinks reception before the performance. There is an “early bird” discount price of £45 (tickets will be £55 after Friday 5 September 2014). To book your ticket and guarantee your place please contact Holly on firstname.lastname@example.org.
We are currently looking for ‘envelope-stuffers’ to help us get these invitations out as quickly as possible! We will, of course, provide drinks and biscuits. Any time anyone can spare would be so greatly appreciated (even if it is just half an hour before a massage!). If you would like to help, please contact Holly on email@example.com or 020 7830 2323. Alternatively, if you are in the Cancerkin Centre and would like to help, just speak to any member of staff.
If you have any questions please contact Holly on firstname.lastname@example.org or call 020 7830 2323.
Darkness at night key to success of tamoxifen treatment
Scientists from the University of Tulane in New Orleans have suggested that sleeping in complete darkness is the key to the success of breast cancer treatment.
The study published in the journal Cancer Research is the first to show that exposure to the light shuts off night time production of the hormone melatonin which is critical for the success of tamoxifen, an anti-oestrogen drug that is widely used to treat breast cancer.
The researchers found that tamoxifen delayed and slowed tumour growth in animals with either high night time levels of melatonin during complete darkness or receiving melatonin supplementation during dim light at night exposure. The study shows that melatonin production is necessary for tamoxifen to work in breast cancer therapy.
David Blask, co-lead researcher, said: ‘High melatonin levels at night put breast cancer cells to ‘sleep’ by turning off key growth mechanisms. These cells are vulnerable to tamoxifen. But when the lights are on and melatonin is suppressed, breast cancer cells ‘wake up’ and ignore tamoxifen.’
Co-lead Steven Hill said ‘Our study does not identify how much light exposure is needed to suppress night time melatonin production, and potentially drive tamoxifen resistance in humans, but we think that it could be as little as the amount of light that comes in the bedroom window from a street light. We are working toward conducting the studies that will answer this question.’